One of the missions of NewG Lab Pharma
(NGLP) will be to develop novel anticancer
therapeutics that extend the life of cancer patients
without compromising the quality of life.
Contribution to cholesterol metabolism and nutrition,i.e., cholesterol reduction methods in food.
Contribution to fundamental understanding of an enzyme (Isocitrate Lyase) function led to potential therapeutic options for bacterial and parasitic infections.
- Contribution to molecular understanding of the genetic disease, Cystic Fibrosis and potential therapeutics for protein mis-folding diseases.
- Contribution to mitochondrial membrane protein bioenergetics: Discovery and purification of a membrane protein called “ATP Synthasome” from mammalian mitochondria. This is the enzyme that provides the energy necessary to fuel numerous metabolic and physiological processes and is an important target for cancer therapy.
Discovery of a small molecule, called 3-bromopyruvate (3BP) as a potent and selective anticancer agent.
Translational research by taking a bench side discovery to bedside therapy. Proof of principle was met for 3BP as an effective anticancer agent. In addition, other independent research includes investigating some metabolites, proteins/peptides, and compounds from natural sources for treating other dysfunctional conditions.